Funded research programmes driving our understanding of Alzheimer's disease, astrocytes and brain metabolism.
The crucial role of brain insulin action in the regulation of systemic metabolism, energy balance, and glucose homeostasis, as well as in the modulation of cognitive function, is well established.…
Astrocytes are brain cells that help, support and protect neurons, ensuring the brain functions properly by providing energy and defending against stress. However, in diseases like Alzheimer’s, these cells change…
Alzheimer's disease (AD) represents a growing public health challenge, with its prevalence steadily increasing profoundly affecting both patients and their families. Despite extensive research focusing on amyloid-beta and tau as…
Cerebral blood vessels are composed of endothelial cells that interact closely with astrocytes, regulating the transport of nutrients such as glucose into the brain. Glucose…
This project investigates how insulin resistance in the brain may link age-related diseases such as type 2 diabetes and Alzheimer’s disease. In particular, it focuses…
The availability of glucose in the central nervous system is essential for neuronal function, and brain glucose levels have been shown to regulate neuronal activity.…
